End plate junction is present between
A. Neuron and striated muscle
B. Neuron and neuron
C. Muscle and muscle
D. Both (b) and (c)
Answer
656.7k+ views
Hint: End plate junction is a chemical synapse junction. It helps the motor neuron to transmit a signal to the muscle fiber which causes muscle contraction. Nerves from the peripheral nervous system and central nervous system are linked with the muscle and work together.
Complete answer:
There is synaptic transmission at the end plate junction or neuromuscular junction when the action potential reaches the presynaptic terminal of the motor neuron. This activates the voltage-gated calcium channels to allow calcium ions to enter the neuron. These calcium ions bind with the sensor proteins on synaptic vessels which trigger vesicle fusion with the cell membrane and release neurotransmitters from the motor neuron into the synaptic cleft. In humans, this neurotransmitter is acetylcholine which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors.
Terminal branch of the motor neuron is thus connected to the target muscle and the movement is facilitated with the help of secretion of acetylcholine. This leads to the muscle contraction and then relaxation with help in overall working of the muscles. The development of the neuromuscular junction requires signaling from both muscles and the neuron's terminal end. Presynaptic motor axons at the neuromuscular junction terminate 30 nanometers from the cell membrane or the sarcolemma of the muscle fibre. Invaginations at the sarcolemma junction are called post junctional folds, which help in increasing the surface area facing the synaptic cleft.
Hence, the correct option is A. Neuron and striated muscle.
Note:
Neuromuscular diseases are referred to any disorder that is associated with the synaptic transmission between motor neurons and a muscle cell. These diseases can be inherited or acquired by the person.
Complete answer:
There is synaptic transmission at the end plate junction or neuromuscular junction when the action potential reaches the presynaptic terminal of the motor neuron. This activates the voltage-gated calcium channels to allow calcium ions to enter the neuron. These calcium ions bind with the sensor proteins on synaptic vessels which trigger vesicle fusion with the cell membrane and release neurotransmitters from the motor neuron into the synaptic cleft. In humans, this neurotransmitter is acetylcholine which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors.
Terminal branch of the motor neuron is thus connected to the target muscle and the movement is facilitated with the help of secretion of acetylcholine. This leads to the muscle contraction and then relaxation with help in overall working of the muscles. The development of the neuromuscular junction requires signaling from both muscles and the neuron's terminal end. Presynaptic motor axons at the neuromuscular junction terminate 30 nanometers from the cell membrane or the sarcolemma of the muscle fibre. Invaginations at the sarcolemma junction are called post junctional folds, which help in increasing the surface area facing the synaptic cleft.
Hence, the correct option is A. Neuron and striated muscle.
Note:
Neuromuscular diseases are referred to any disorder that is associated with the synaptic transmission between motor neurons and a muscle cell. These diseases can be inherited or acquired by the person.
Recently Updated Pages
Which of the following graphs shows the variation of class 12 physics CBSE

Draw a labelled diagram of the human male reproductive class 12 biology CBSE

Describe the experiment to compare the emf of two cells class 12 physics CBSE

What is standard hydrogen electrode

What is conventional current and electric current class 12 physics CBSE

2Bromopentane is treated with an alcoholic KOH solution class 12 chemistry CBSE

Trending doubts
Draw a labelled sketch of the human eye class 12 physics CBSE

Which are the Top 10 Largest Countries of the World?

A member of Simon commission later became Prime Minister class 12 social science CBSE

Draw ray diagrams each showing i myopic eye and ii class 12 physics CBSE

Give one example of a reptile that is viviparous class 12 biology CBSE

Which is the correct genotypic ratio of mendel dihybrid class 12 biology CBSE

